Based on standard US drinks, 1-2 drinks does absolutely nothing. 6-7 is enough for a decent buzz with no noticeable effects the following morning. At around 10 it starts to get uncomfortable and by 12 the room starts spinning. At basically any of those levels I’ll have no real hangover beyond a dry mouth at the extreme end, unless the drinks were overly sugary, like a sweet wine or sugary mixed drink. In which case I’ll have a mild headache as well.

The only real exception to that is tequila (in any amount), or anything with agave in it. I am allergic to agave and it leaves me with a sore throat and a headache that makes suicide seem like a perfectly reasonable thing to do. Though in terms of intoxication it acts like any other alcohol of comparable strength.

I also don’t drink often, 3-4 times a month at most. I have a fairly high baseline tolerance. That also extends to a lot of meds, particularly anesthetics and anxiety meds, which has been a problem in medical environments.